Pretty funny. As you can tell, a query like this will provide you with three points of view.
It really depends on what your engine wants. The smaller venturies and throttles will generally help bottom (street). They may help throughout the range when fuel distribution is not ideal or the engine really likes a bit more atomization of the fuel.
The 3310-2 is about as good as you can get for a vac secondary 4150. I'd spend time tuning that before trying another carb. If its unmolested, jet and spring changes are about all it should need.