Is there an appriciable difference between big name tools?

I think a lot would depend on who is available in your area and will continue to be available....many years ago (1975) I bought into the Cornwell system...now that I have moved to a new location, I cannot seem to locate a jobber. I have broken a couple wrenches and sockets...unable to replace the broken one, I have retired the sets and replaced with tools I can get my hands on readily...guess I am anal about matching sets...