The MDS system can run just fine with a carb. The carb can run across an entire range of RPM and CFM so when MDS is active, the CFM are cut in half. The principal of carb operation relies on the CFM rate to pull in the fuel so it will operate just fine.
The tricky part is turning the MDS on at the right time without a PCM to control it. Deactivation occurs during the compression stroke of each cylinder, after air and fuel enter the cylinder. Ignition then occurs, but the combustion products remain trapped in the cylinder under high pressure, because the valves no longer open. No air enters or leaves. During subsequent piston strokes, this high-pressure gas is repeatedly compressed and expanded like an air spring, but fuel is not injected.
If you use a solenoid to deactivate all the cylinders at the same time, some will turned on at the wrong point in the stroke. You risk having some cylinders closed under incorrect pressure that then may act as an air brake pulling power off the engine creating an unbalanced engine rotation.
