Engine pre run oil pump

What I know is that nearly every engine I have ever owned eventually develops bottom end noise for a second or two at startup. My 2014 F150 with 80,000 miles and synthetic oil has it now after religiously warming up before driving and oil changes at 5000 miles whether it needs it or not. I drive 100 miles round trip to work and back. Sure engine oils and fuels have anti wear agents in them but when the rods and mains aren't in a fluid floating state, scuffing can occur... that is what I want to avoid. I would think that in a higher compression motor the scuffing effect may be even worse.
Interesting.... Have any of them been torn down and looked at what has actually worn? I'd suspect piston slap first, just due to bore and piston wear (but a good synthetic ought to prevent that). And lifter noises 2nd....and maybe advanced ignition timing to aid startup with modern ECM's? And again, if it is indeed the rod bearings, it is just about impossible to know if the wear came from start-up or just running. Knowing how incredibly well a good synthetic protects bearings, I just find it hard to think this is just a startup oiling matter.

FWIW, I have not experienced anything like that type of noise at 80k miles in a whole bunch of different engines... and my hearing and ability to hear and detect small things like is pretty good. I don't rev the motors at startup, maybe raise them them 1200-1500 RPM at mos, if at all.

You may be onto something though for really high powered engines when you just simply get a lot of chamber pressures all the time; there is a purpose for the Accusump type of product in some situations. I just can't see it based on my own experience with typical factory car engines.