'70 Dart 392 Project; what direction?

I've seen the relocation brackets centered, and offset to one side by leaving one side of the frame rail in tact. Obviously if you offset them, you will have to deal with the offset on the rear rail, which may require additional fabrication beyond just drilling a hole and welding a sleeve into the rail.
Sorry I was asking about tire placement in regards to how narrow I cut my axle housing not in relation to where I relocate my leaf springs. Do I center my rubber in the wheel well or do I push it out as wide as possible?

I’m not too worried about cutting into the frame rails. The factory frame steel seems fairly flimsy and the RMS brackets should give it some extra support, though I may weld an additional side plate to mimic how USCT has their design.

Mike