Can small block oil pump be replaced without pulling the engine?

Well I DID just this on Vixen a few years ago before I swapped the 225 in. I resealed the pan, replaced the oil pump, rod and main bearings and put a new timing set in her original 170. I could have done it all in the car, but rather than roll around on the ground, I pulled the engine and transmission both. It took Kitty and I less than an hour with hand tools and I had the engine on the stand. With all the other work you have to do to do it in the car, you're going through the same amount of labor.

I imagine that /6 vs V8 would also change that operation substantially. OP has a magnum V8.

My car’s a bit of a special deal, there’s no way the 340/T56 will come out the top with that road race pan. When I put the engine in from the top I couldn’t even have the flywheel attached because of the combination of that oil pan and spool mount K-frame, it has to go straight down with no angle at all. Only way the engine/transmission comes out together is out the bottom on my car.

So yeah, the difficulty level of pulling the engine or doing it from the bottom will depend a lot on what components and aftermarket parts are used.