Would this set up be desireable in my 66 Cuda?

Well, is it a 318 w/340 heads? I'd say not to terribly fun myself. Theres also no cam specs or comp. ratio listed. It could be a dead ratio and to big of a cam.

Alot of parts listed are desireable. 340 heads, LD340 intake etc...
The parts alone are not worth the price. The 340 parts are a mismatch on a 318 unless it has zero deck pistons for a decent ratio.
With desireable cam specs coupled with a high stall converter and rear, it could be fun.

You'll need to inquire about the comprsion ratio and cam specs.
Your also probably better off tossing the exhaust manifolds for headers. Speaking performance wise, it'll be a good power upgrade for the most part, part dependent.