Base/clear coat or single stage paint
FWIW, my car was orignally painted with Dupont Chroma Base/Clear in Sublime back in 2000. I have since had to do some rust repair (this was my first attempt at body work and rust repair) on both sides of the car. I still had a quart of Dupont Chroma One single stage that I had used for under the hood and in the trunk. I have spotted painted the rust repair with this paint figuring I would clear it. It came out so good that I just wet sanded wet sanded and buffed the repair work. You just can't tell where the transition from single stage to base/clear is. There just is no difference with a bright non-mettalic like Sublime.
I wouldn't hesitate to paint a non-metallic car in single stage. The quality single stage paints have all the UV inhibitors that are in the clear so fading won't be an issue.