I will be running the AIS Stage 2 system..............with multiple nozzles and about 15lbs of boost. 410 Stroker 9:1 Compression with Iron Heads and a Air to Water intercooler with a Heat Exchanger that will have 2 10" Fans on it and a Ice Box in the trunk that will be used for racing only.
There is some good information here about where to mount your nozzle or nozzles.....
http://www.alcoholinjectionsystems....-My-Water-Injection-Nozzles/article_info.html
Running 16lbs of boost you might want to consider running 2 or 3 nozzles.
What meth system are you running?