Can a garage be too big?

We had our house build and like a provious post, I had the builder add to the garage as I wanted it set up to build cars. Wife didn's squak as she got the rest of the house. I wish i would have made it a little bigger but it works great for the work i want to do on my cars. I also have a 36 X 48 shop full of snowmobiles but that is another story. I am now trying to figure out the paint booth aspect of all this at home.