The simpler (not necessarily better) route would be a 4-bbl, blow-thru modified Holley or Carter on an aluminum manifold from Offenhauser, Clifford, or Cain (out of production, Australian,) I think.
Maybe you're a Weber guru, and could deal with the proper fuel curve issues in a blown application with that carb, but if you're NOT, I would avoid that particular combination because of the difficulty in building an air box (bonnet) for that carb and getting it tuned properly for forced induction.
Lots easier, with an American 4-bbl, seems to me. But, that's just my opinion...:shaking2:
