Can a Ford 8.8 handle a big block?

Stepper said
Given the going rate for 8 3/4 rear ends, I'm seriously thinking about the Explorer 8.8 rear end swap. But I have no idea if it would handle my plans for a 400 to 451 stroker build.

The car will be mostly street and I may do a strip every now and then, but it's mostly for street and cruising.

I know the 8.8s were used in cobras etc, but has anyone used one behind a mopar big block?

I have a 600+ RWHP 2006 Charger that had a prototype 8.8 rear that held up fine. I was doing consistent 1.4's in the 60 with a 4300 lb car too. Now granted it was on the housing/center carrier and had a tru trac in it as well. The axles housing were cut off because the car had half shafts. But I never had any issues with the actual 8.8 center section.