1965 HIPO 273 intake manafolds.. Any good upgrades??

I suppose you could use a pair of small AFB's or AVS's.

Would it be any faster than a single 4bbl? No. Would it cost twice as much? At least. Fuel economy hit? Possibly. Look cool? Heck yeah!
X2 except I would say "yes" on lower mileage. The only other thing to consider is if it will fit under the hood without cutting. Air cleaner(s)? kickdown linkage? Even if it looks cool, if it doesn't work right, it will grow old in a hurry.