Holley Strip Dominator for the street?

I think if you have a TQ, it might help low end efficiency with the small primaries. Those intakes do in fact have the Thermoquad opening for the plenum... Open up the secondaries though and it will run with anything.

Single plane/double pumper/4 speed with gears seem to work OK on the street. Would probably not be good with an auto due to converter slippage. You actually might need more gear, 3.91 would likely be your minimum starting point. Mileage? We don't need no steenkin' mileage!

As a similar example, my buddy has a little Rambler American sedan street machine. He runs a Torker with a 750DP on his AMC 390. He rows a 4 speed, has 4.10 gears and a .495"/300+ degree solid cam. That thing is pretty wild on the street, fishtailing all over the place at the blip of the throttle. However, it seems like it drives alright when his foot is not in the radiator.