Eagle Cast Stroker Crank- Problems or No Problems?

I gotta ask guys. Why use a cast crank anyways? I mean most people run an internal balance engine and the short block is the most important part of the engine. So you can run a set of cheaper heads (say 1.88 instead of 2.02 because of money, also say you had the 1.88 laying around) you can bolt on a set of heads on later and don't have to pull the motor to do it. Basically I'm saying don't cheap out on the bottom end and over build you motor for the intended power level so you won't have to worry about breakage. This is what I did for my 340 (I can post build spec/parts if you guys want) which makes about 400 HP but all parts are rated for much much higher HP.