Carb suggestions for 360

Yeah carb tunning was never my strong point!!! I quess its time to dig out the Holley book and do some reading. Dont even know whats in the carb as far as jetting or anything. Any thoughts on a good starting point to work from. Also should I think about swapping out the throttle plates so there not drilled, only primarys are drilled. Think that could cause tunning issues?