small bolt pattern wheel question

Can I adapt small bolt pattern wheels with the 4" pattern that fit drums to my 4.5" large bolt pattern disk brake hubs? Since I am talking about stock steel hub cap wheels, can they be redrilled to match the larger and wider spaced lugs? Thanks :-D

No I don't think you will have a flat surface to do it and for the lug nuts to seat. But I could be wrong as I have never tried.