Who started building there 408 stroker today? this guy right here!!!

it would take less time to spool a tt setup than a one BIG turbo setup
Like Mopar426 said Twins is spool up faster, meaning power coming sooner. As far as space is concerned you can get a reverse style turbo (different from the standard turbos you usually see) so you can save on room and get that nice tight fit.
There is a member here that as a picture of twin turbo mounted on a sb for his avatar, might want to talk to him (his name escapes me at the moment).