stroker life span?

well im not really on a small budget. Im fine with dropping 7k into my motor. I just want to do it right the first time and have it last. i thought about just building up a 360 but it just isnt enough. I really want a streetable 375 rwhp. if the stroker wont last past 40k miles then I either need to go big block or forced induction. I just really want to do it right the first time.