Mopar in a Mustang ...

Actually they did come with a big block 390 option back in 68, friend of mine had one. Changing some of the plugs was near impossible but the motor did fit. Not sure about the difference in size though, 429 hemi or 427 cammer are probably wider
Boss 429 is a different series 390 is an FE and the 429-460 were "385" I think, not to mention the boss heads are a ton bigger. As to the cammer there was one in a Thunderbolt, think it was a Mickey Thompson car so with enough grease....Pretty sure someone is making reproduction ones if you got the $$$. Unless you have to have a big block how about a http://www.summitracing.com/search/...-427-C-I-D-535-HP-Crate-Engines/?autoview=SKU
351w based 535 hp 427?