I don't know how anyone could answer that without very careful double-blind dyno tests, and who would pay for that? I work in aerospace testing and we don't have funding to study things to the nth degree. I suspect a 1" spacer would have negligible effect on air flow and atomization of the fuel. The main thing is insuring you maintain the carburetor to intake match, such as having a 4 hole spacer if a dual plane intake.