2nd round of primer

I'm working on my 2nd round of primer. The first round was 1 coat of epoxy followed by 2 coats of 2k high build. After blocking at 220 and guide coat. Im ready for the next step. Im fairly new at this but i believe my next step is to primer again with 2 coats then wet sand at 400 for my sealer and top coat. My question is the first time around I didnt use any reducer. Should I use some reducer for the final coats? When yall yet sand do you use just water or do you put some soap in the water?​