Holley 600 Double pumper on a stock 318 Auto?

Yes. As stated above....your gonna have to get used to driving it with a double pumper.....they are mechanical secondaries and can BOG under a load.

On the Forced Induction 318 with a automatic trans it will be great.

You going with a MP T70 single setup?
I have been playing with this idea for years with similiar expectations.
I already have most of the parts, Except for the Turbo and Hotside piping, including a 4777 Holley 650 DP...that is already Blowthrough modded.

That's the idea. I can source the parts pretty cheap and I'm familiar with the turbo side of the equation. Tuning the carb will be a learning curve but nothing I can't handle.

500rwhp will put the car @ low 11s high 10s with good street manners.

I'm thinking max boost of 15lbs on 93 octane should get it done.

727 trans and 8 3/4 rear should be good for that power rating from what the forums say. I'm sure there will be a few things to help them live though.