Edelbrock Street Ram on a 408?!?

The obvious difference between the one you pictured and the TR-5 in the link is the plenum volume. There are members here running them that seem to have had success on the street and can maybe give you some short cuts to tuning. Been around a few on big blocks, but i've only personally run one many years ago on a 331" engine. Had decent drivability, but i bought the carbs from a previous 2x4 setup so i didn't mess with them too much. The ironic thing about making them crisp and clean on the street is to go milder on the cam and carb size. Sounds counter intuitive for a race manifold, but you need a small plenum and as much vacuum as you can get for a decent signal to the carbs. There are always comprimises though. The smaller plenum puts the carbs closer to the ports which helps signal, but with vacuum secondary carbs the primaries are opening right over those runners which can cause distribution issues on others until the secondaries are open. Then there's your accelerator pump shot that has to be right for the plenum volume you have. Big plenums require huge pump shots and tend to run very rich in city/cruising situations. If you will take the time to tune everything, then go for it. Unless you're going to use a roller cam, you might want to break in the new engine with a single four. Would be easier in my opinion. I would use the small plenum manifold you showed with the 450 Holleys Rumble suggested and even thought strokers eat duration, i would scale back the intake side duration and go to a wider lsa on the cam to help streetability. Just some rambling thoughts..:D. Good luck.