Anyone running a Paxton on a 340?

Crank is fine, did you use full groove main bearings? As this supplies full time oiling to the rod bearings.

A cam some overlap will be ok as it cools the combustion chamber.
I ran a MP .509 lift, 292 duration, 108 overlap cam in a Roots blown MP shortblock with Edelbrock heads. The cam was in there and I ran it. LOL

Im pretty sure I had 9.5to1 CR and I ran it on the street most of the time.
Always on pump gas and kept timing around 32 degrees.

A wide 114 LSA is great for a track car and some street use.
On the street a 112 LSA seems to work well.