12 Second N/A Slant 6?
How about starting here for induction/exhaust?
Long, equal length intake manifold runners
small diameter, long primary tubes on the headers for maximum torque. Should work well W/410 gears on 28" drag radials.
I look at this engine as a trio of stroker Harley engines so 5000 RPM shift points (40 & 70 MPH) would be ideal W/the ability to wring out the top gear to 5500. Should hit about 112 MPH.
That always worked well with my 86 inch Panhead W/a 4.520" stroke & 3.465" bore.
That ain't far off from what the slant 6 would be W/a slight offset grind on the crank & 89mm 2.2L pistons.
3.5" bore X 4.175" stroke.