12 Second N/A Slant 6?

PowerWagon896 said

I'm wondering though. Would I be better off going for a large 2 bbl carb over a 4 bbl? Would the trade off in HP be too much to gain some drivability?

I did once have a Carter WCFB 4 bbl that worked really well on my 301 '57 Chevy SB.

It was simple, trouble free & got decent fuel millage.

I see the WCFB recommended in some articles. I would feel pretty comfortable working W/one of those.

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To get a 2 bbl to flow enough,the barrels would have to be pretty large, and that hurts throttle response. A WCFB is an "obsolete" carb (a little hard to get "tune up" parts). A mild slant works well with a 390 Holly, but that is small for what you want to do. 500 Edlebrock is viable. as is a 500-600 Holley. I have never tried one but I really think a small "Q" Jet or Thermoquad would be the ticket. Especially if your willing to tinker with it.