Absolutely. Candy apple red is a multi-stage color too, each stage effects the final color. If anything, candy apple red is MORE susceptible to changes because of the primer color than a standard solid color.
and actually very impractical for that reason. Looks fantastic but very difficult to spray as you're building color with every coat so you have to walk the car, can't shoot it by panel or partial panel. If you get into a fender bender forget about being able to match the paint, if you use a true candy. House of Kolor has a line that mimicks candy so it looks similar but is much more forgiving.