Well I'm running a stroked 360 on the stock OBD-I PCM in my 1995 Grand Cherokee. It runs well, am I leaving power on the table by not being able to tune you bet. But it still works. There are a couple ways to trick the PCM.
My best run was 13.344 @ 101.44mph. And thats in a 4x4 with a 3" lift and 31" tires with stock gearing.