There is discussion of the effects of (apparently) less-than-optimal intake manifold placement and angle of injectors in [ame=http://u225.torque.net/cars/tech/Papers/900852.pdf]this SAE paper[/ame] by Chrysler see page 9, "Intake Manifold" section. If you take a look at Figure 17 (zoom in), the injector placement and angle on the Chrysler 2.2 & 2.5 MPFI engines (all turbos + the '93-'95 FFVs + the '91-'95 Mexican non-turbos) looks "wrong", but those engines run well.
