Taking apart the floor/firewall seam

Don't know how much you have pulled apart.... I'd only drill them if you are going to be able to weld them there. I did drill some from fender side, a few of them were gone -had a section of rusted firewall that I had to replace. I didn't have engine out at the time so I don't think I was able to get on them all. I just welded some of the seam from inside
Mine already had the filler removed, but the firewall fold has a 90* lip that the floor pan fold sits on. Mine was just spot welded. Drill them out in the engine bay and wheel well. My dart had 5 or6 on wheel well side one the same on the engine bay.