Off set crank grinding

Good question... Im tuned in... I hear of chevy guys doing this and running honda rods. I know a guy who is running a small block 400 chevy crank (w lots of machine work) in a mopar X block w 4.1 bore and W5 heads (he works at the machine shop so all work and hrs are only time. He CLAIMS the chevy cranks are lighter, stronger, with many more rods and pistons to choose from. I believe the 400 is a 3.75 stroke. I know his combo works pretty well. He is turning 5.90s in the 1/8th in an all metal Duster. Not so sure, id want to work on it, but what ever works I guess