Off set crank grinding

I wonder if this would provide any opportunities for those old racing cranks?

Say for example the 273/318/340 main journal sized - forged 'yellow steel' 3.51" crankshafts?

Do people ever go beyond chevy & use the 4340 honda rods any? Or does that require the use of custom pistons outside of the +4.00" bore range? Perhaps with an early 318 overbored into 4 inches..?