Big Block Strokers - How big should we go?

I had a 440 Source rotating assy and sold it cause I didn't like the crank quality. Now have a Eagle crank and rods, 4.250 / 7.100 with chebby journals. Went with 4.500 bore on the World block to unshroud the valves. Worked OK with 10.720 deck. Custom pistons, oil ring is not "in the hole".