Getting the most out of a low comp 440

As you said - it's the combination that makes or breaks the engine and truck. And - combinations are as varied as trucks and cars...
I suggested forged pistons because in a towing rig (even "mild towing" there may be a tendency to try and ping if you get some bad gas. Low compression or not. Forged will put up with more abuse... hence the recommendation.
But - if you want to leave it along that's fine too. In my opinion I'd spend a little more for a more modern grind that's made to work with low compression. Either summit cam will work. But I'd run a Comp XE262 and a set of MP Hemi springs. Fairly cheap and charming and will make more steam than the Summits with no downsides.