Thinking of changing direction with my engine. Opinions needed

I have a fresh 340 that I just broke in but have an issue with one of the heads. Since I will be pulling the top end off of the engine I am considering making some changes and installing edelbrock rpm heads, RPM airgap intake and a 750 holley avenger carb. With the iron heads I had calculated them to be 9.25:1 compression. With the edelbrock heads it would be 9.6:1. Would that ratio work good with aluminum heads? Generally I see around 10:1 used but that just may be to wring all the power out of it on 93 octane at the pump since the heads run cooler. It does have a six pack setup at the moment but I am considering selling it in favor of easier tuning. Throw me your opinions.