Fuel restriction w/ 6an line?

The pressure doesn't change from the hose sizing

It will ABSOLUTELY change from hose size.

How much? Again, I am not sure. Probably not a whole lot in this particular case.

In any event, whether its 1 psi or 100, you will have some difference in pressure if you install tubing that will physically alter the volume of fuel flowing through it after it's already been regulated to a specific pressure, all else being equal.