I ran mine occasionally on the street locked out at 40. More or less just to putt to the track and back home when my trailer wasnt available, it was tolerable. She's a hard starter for sure. I have my ignition on a switch to get it spinning. i should really have a starting retard assist from MSD. I'm not sure why on a street car anyone would tell you to lock it out. guys thats dont understand a vac advance sometimes just use the mechanical, but 22 initial seems really high. i'm thinking fully advanced around 32, should idle around 10-12. I honestly dont think you'll see any performance gains from a lock on a street car. now making sure your fully advanced timing is right....thats worth looking into.
