225 carb change

I have a 82 d150 with 225 and a carter carb I bought a napa remand (junk) have replaced so many times that they wont do it anymore. the flotbowl empties overnight into the motor, I have rebuilt it twice with same problem, new fuel pump, same, any ideas?
now to the question...can you put a holley (I can get new) on it, or do you need manifold to use the holley? any help is needed.....joe