68 truck 318 cam. How big can i go?

It's my understanding the truck engines were lower compression.

No, they are a better engine, most had forged cranks and good internals.
Probably the best 318 I ever had was in a rusted 69 D-100.
I added a old 340 manifold with a AFB, and a set of headers.
It had a flat bed with 3.91 sure grip, it would fry the tires forever.

You are bringing back memories, I traded a 4 door dart and $50 for the old truck.
Driving it home, it started raining hard, I ended up soaking wet clear to my crotch, the floor board were super rusty with big holes.

Patched the old girl up, drove it for 2 more years until it was really unsafe to drive.
Put the motor in my first duster, ran it for years.
After building a hotter motor for the duster sold it to a guy because it was a matching year motor for a boat he was restoring.

You could not blow it up, I think the stock cam must kept the redline down where it did not come apart.