Fuel Starvation / Mechanical Fuel Pump

Looks like your boiling the fuel just before the pump running that line so close to the header. Does it act up when it's warmer outside? I ran my line up on the inner fender.

X2 big time.
It's not just that number two header either, as the heat from all the pipes will build up all along that fuel line the way it is.
Header wrap would help, but I hate seeing that stuff all over the place.
Heat shield or insulation is about the only temporary solution to that issue, but rerouting would be the way to really take care of it.

Just an FYI I use 1/2 heater hose split longways around steel lines that get a little close to the headers.
It allows an air gap between the hose and the line and seems to work well.
Maybe that would help your situation until you can reroute.