single stage vs base coat clear

Going to drive the car to the grocery store?
I've always used single stage Sherwin Williams acrylic enamel with good results.
I've never used base coat clear coat except one time to repair a dear hit to my wife's Voyager. Pained the whole panel.
I can touch up small areas with single stage. Can you? Can that be done the clear coats?
Metalic is a little harder to do touch up. Have to keep it mixed in the gun to blend right.