Trouble starting

I am getting fuel up to the rail, I pulled the connector off before and it sprayed fuel everywhere and I can hear the fuel pump prime as well. I can only think that perhaps the injectors aren't seated properly? 6.1 rail on a 5.7 but still the original 5.7 injectors.

You need to check that the pcm is firing the injectors , use a noid light to check at the injector connector to make sure the pcm drivers are firing the injectors off and on and also makes sure you have power to the injectors.

A video explaining checking injector wiring:
[ame="https://www.youtube.com/watch?v=FAipVwCdwSQ"]Fuel Injector Noid Light Testing - YouTube[/ame]

If everything is good there , you may have bad injectors from setting too long.

If your injectors are getting proper signal and able to turn your noid light / injectors off and on. You can remove the fuel rail with injectors, injector wiring and fuel supply line attached and turn the engine over and look for a spray from the injectors to make sure they are working.
Just be sure to remove any chance of spark near the fuel, unplug the coils.