Radiators: Is 22" enough for 400 HP?

For the OP, the issue of sitting in traffic will likely be the worst case. You might get by with a 22" radiator with a very good OEM type fan and shrouding. But I see no good point in taking the chance and ending up too short on cooling capacity and having to buy twice. It is like cutting lumber: too short is hard to fix; too long is easy to fix.

Yeah, I'm starting to think that maybe it's better to play on the safe side and go with the bigger radiator.