Radiators: Is 22" enough for 400 HP?

That actually looks pretty good! That's a slant 6 shroud flipped over. Are you using the trans cooler in the radiator? I'm curious if the fittings are blocked by the lower curved portion of the shroud.

Also, how tight is the shroud with the top and bottom tanks?
OK, thanks for that info on the shroud type. The gaps are maybe 1/8" top and I think the same at the bottom. And yes the in-rad trans cooler is being used; the shroud is fully clear above those. As said, the PO got this; we just improved the mounting.

The fan is not centered in the shroud; it is set towards the top of the shroud opening. But I never think that effects much; the draw problem is mainly through any gaps between shroud and rad along the sides.

BTW, we are going to change the belts.... the double belts over the water pump pulley and then AC compressor puts the slack side of those belts pulling on the water pump and fan pulley, which makes them slip really easy and they need to be tightened way too much. So we will change the water pump to drive with the alternator off a single belt and direct drive the AC compressor alone. We'll probably go to a 15% underdrive crank pulley; when get to revving to 6k or more, things are just gonna be spinning too fast.