How much horsepower is too much for small bolt pattern stuff?

I would say "a bunch." There was a thread somewhere else referring to the 4 bolt Ford stuff....earlier Mustangs and so on. I've forgotten how fast some of them claimed on the 4 bolt pattern.

Thank you for the replies gentlemen. I guess I'll stick with my 741 case and my small bolt axles. Should be around 400 hp from my 340. Sounds like my rearend stuff should hold up fine. Thanks again, everyone.