Edelbrock Carburetor tuning question...

That's probably not a bad idea.
My Edelbrock experience is that they're fine, if not a little rich, at full throttle, but lean on the primary and idle circuits. Therefore, full throttle runs probably won't help. Going up four jet sizes on the primaries is a big swing on one of these. Of course, all cars are different.

Alternatively, the manual choke models are richer from the factory, and they tend to be TOO rich on the primaries.