Front vs rear wheel sizes for best handling

I'd say yes in the tire diameter being equal. The width shouldn't (IMO at least.) be to different.

What I did on my wife's '67 Cuda was 26 X 8 up front and 26 X 10 at the rear. Basic QA1 shocks. New rear leaf springs with a 1 inch over bend.
Front and rear sway bars coming.
Current bushings are rubber. PST poly graphite for the future.
(Loved it in my E body!)