Super tuning car runs good shooting for great

For the OP, we are running vacuum advance on my son's 340 on the street with a very similar combo to yours:
- flat top KB's, zero decked
- 63 cc Edelbrocks, quench gap at .040-045"
- true SCR at 10-10.2, DCR at around 8.2-8.4 with a Crane Z-268 hydraulic flat lifter cam; cranking compression averaging at 158 psi (that number is right where it should be)
- Initial at 15 and total at 35-37
This engine has yet to ping once, running 93 octane Shell premium, or no-name ethanol free premium.

If you are aiming for better fuel economy, then look into an AFR gague and work your AFR up into the 15's at light cruise.