Numbers matching, no. Correct date code possibly. 65 mopars did not have matching numbers on the engine to chassis/body. If the engine date code is prior to the car build date (usually 1 or 2 months) it would be correct.
I have two 66 "A" bodies, that were born with V-8's, but have slants in them now. Picked up a 273 2bbl "core" engine with a early 66 date code, so I could put them back to the original configuration, if I desired.